Silymarin, an extract from milk thistle seeds, has been used for centuries to treat hepatic conditions. Preclinical data indicate that silymarin can reduce oxidative stress and consequent cytotoxicity, thereby protecting intact liver cells or cells not yet irreversibly damaged The product has been used to increase milk secretion, relieve menstrual cramps, lessen depression, decrease gallstones, and jaundice as well as improve functions of the liver, spleen, and kidney. its potent antioxidant, antifibrotic, and anti-inflammatory properties. they prevent the propagation step of lipid peroxidation by scavenging peroxyl radical intermediates in the chain reaction Indeed, oral consumption of silibinin was associated with a significant increase in both glutathione S-transferase (GST) and quinone reductase (QR) activities in liver, lung, stomach, skin and small bowel in a dose- and time-dependent manner silymarin reduces insulin resistance by affecting insulin receptors, and by stimulating factors effective in protein synthesis, it is effective in repairing damaged liver cells and restoring the normal function of these cells. The product is a pharmaceutical grade and is produced as a yellow powder.